BJC Careers

HLA Technologist, Nights *Sign On Bonus Eligible**

Saint Louis, MO

Job Description

Job ID: 1175056
Employment Status: Full-Time
Regular/Temporary: Regular

Your Career. Made Better.

Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in Missouri and is ranked as one of the nation's top hospitals by U.S. News & World Report. Barnes-Jewish Hospital's staff is composed of full-time academic faculty and community physicians of Washington University School of Medicine, supported by a house staff of residents, interns, fellows and other medical professionals. Recognizing its excellence in nursing care, Barnes-Jewish Hospital was the first adult hospital in Missouri to be certified as a Magnet Hospital by the American Nurses Credentialing Center.

No other organization offers an opportunity for exploration and discovery like Barnes-Jewish Hospital. As a laboratory professional with Barnes-Jewish Hospital, you¿ll have exposure to the most advanced testing protocols and processes in medical diagnostics, and one of St. Louis¿ widest varieties of disciplines and specialties in laboratory careers. Our full-service, 24/7 laboratory is known for its leading-edge technology and the most progressive clinical techniques in practice today. You'll be working with the best, in a supportive atmosphere that will encourage your growth and advancement. Plus, you'll have opportunities to share your skills and knowledge by participating in clinical trials and research in conjunction with leading organizations such as the Washington University School of Medicine.

Join Us!

Role Purpose

Performs specimen processing of human biological material for specialized high complexity molecular and histocompatibility testing which requires a knowledge and understanding of quality control, instrument maintenance, and the ability to understand and communicate scientific principles related to molecular biology including nucleic acid extraction, PCR, SSO, SSP, sequencing, antibody test analysis, and crossmatch interpretation. Maintains appropriate documentation of all activities as required. Demonstrates good laboratory practice.


  • Performs routine cleaning and maintenance on complex and sensitive molecular equipment with an emphasis on clean technique. Operates complex molecular instrumentation for the purposes of patient testing, calibration, and validation of the quality of the assay. Delivers precise, timely, and accurate laboratory results. Uses understanding of molecular biology to troubleshoot QC, abnormal patient results, and instrumentation. Identifies root cause and makes suggestions for short and long-term solutions, as necessary.
  • Adheres to strict quality assurance practices in order to maintain the highly sensitive environment required for molecular testing techniques. Prepares stock solutions and reagents following standard operating procedures and quality control procedures. Conducts quality control testing of solutions and reagents and records results accordingly. Analyzes quality control data for trends and identifies deviations from the accepted standard.
  • Ensures testing is ordered and billed correctly. Maintains records for batch testing to include patient information, controls, quality indicators, lot numbers, and details on any manual sample manipulation conducted.
    Provides laboratory testing services for a robust transplant program. Manages the primary data analysis and interpretation of analytically complex transplant patients and quality control test results. Records results through the laboratory computer system accurately and in a timely fashion.
    Reviews patient testing runs ensuring data is of the appropriate quality and controls perform as expected. Issues patient reports and communicates any potential assay performance issues to management. Communicates results, verbally and electronically, to transplant physicians and coordinators.
  • Identifies the opportunity for performance improvement activities. Leads new assay validations, both FDA approved assays and Laboratory Developed Tests, to include data analysis, troubleshooting, assay optimization, and drafting validation documentation and new testing procedures.
  • Provides training for new laboratory personnel, students, residents, and fellows in methods, procedures and use of equipment and instruments specific to the assigned area. Communicates with nurses, clinicians, residents, and fellows as it relates to in-house and send-out testing practices. Clarifies testing questions including specimen type, stability, performing laboratory, and methodology. Oversees hands-on laboratory work for residents and fellows and provides guidance on data analysis and patient resulting. Performs testing for deceased donor transplantation including the preparation of virtual crossmatch forms. Enters HLA data into numerous solid organ and stem cell registries to facilitate transplantation.

  • Minimum Requirements



  • Bachelor's Degree
  • - Physical/Life Science/related



  • <2 years

    Supervisor Experience

  • No Experience

    Licenses & Certifications

  • ASHI Tech or equiv


    Preferred Requirements and Additional Job Information


    Licenses & Certifications

  • ASHI - Specialist

  • Benefits Statement

    Note: not all benefits apply to all openings

    -  Comprehensive medical, dental, life insurance, and disability plan options
    -  Pension Plan*/403(b) Plan
    -  401(k) plan
    -  Tuition Assistance
    -  Health Care and Dependent Care Reimbursement Accounts
    -  On-Site Fitness Center (depending on location)
    -  Paid Time Off Program for vacation, holiday and sick time

    *Pension does not apply to Memorial Hospital, Memorial Hospital East, Memorial Medical Group, Alton Memorial or Parkland Health Center

    Legal Statement

    The above information on this description has been designed to indicate the general nature and level of work performed by employees in this position. It is not designed to contain or be interpreted as an exhaustive list of all responsibilities, duties and qualifications required of employees assigned to this job.


    Equal Opportunity Employer